Beneficial effects of probiotic microorganisms. A review
نویسندگان
چکیده
The aim of the present study was to describe the beneficial health effects of probiotic bacteria, manifested by inhibition of growth of pathogen microorganism strains and that of their colonization of the gastrointestinal tract of humans. The primordial mode of action by which a probiotic eradicates a pathogen can be facilitated by the production of antimicrobial substances such as bacteriocins, organic acids, and hydrogen-peroxide. Lactic acid bacteria and pathogens compete for receptor sites at the intestinal surface. Competition for these receptors will diminish the opportunity for pathogenic colonization and thus protect the host from infection. Many of the probiotic effects are mediated via immune regulation, in particular by the control of the balance of proinflammatory and anti-inflammatory cytokines.
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